Because I'm pasting the highlighted code into Blogger, I can't use the CSS it generates by default, so I use the "noclasses" option:
$ pygmentize -f html -O noclasses -o file.html file.py
And then I can paste the contents of the html file into my Blogger post's HTML.
Actually, on Mac OS X I can save a step using:
$ pygmentize -f html -O noclasses file.py | pbcopy
And then paste directly into Blogger.
Update: the following command-line allows me to pygmentize the Python code in the clipboard (without having to create a file for it):
$ pbpaste | pygmentize -f html -O noclasses -l python | pbcopyAnother Update: it occurred to me I could use the above (updated) command-line in TextExpander (see A TextExpander snippet to paste quoted text and A tr.im TextExpander snippet that works for me) to create a snippet that pastes a "Pygmentized" version of the Python code in the clipboard: